Cannabis and Neuropsychiatry: Benefits and Risks

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  • Relative to placebo, cannabinoids are associated with only modest benefits for chemotherapy-related nausea and vomiting, small and inconsistent benefits for pain and spasticity, and inconclusive benefits for other indications.
  • In randomized controlled trials, cannabinoids increase the risk of total adverse events, serious adverse events, and dropout due to adverse events. Cannabinoids also increase the risk of a large number of specific adverse events.
  • Cannabis use is associated with a range of short- and long-term adverse consequences, including impaired cognition, traffic accidents, dependence, respiratory conditions, psychosis, and possibly cancer. Use in adolescence may have adverse implications for psychosocial adjustment and vocational success.
  • Current strains of street cannabis may have higher potency and may hence carry higher risks than strains evaluated in former research.

Cannabis and Neuropsychiatry, Benefits and Risks

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